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Scientific Breakthrough in Fibromyalgia Mice study 5nvklj





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Scientific Breakthrough in Fibromyalgia Mice study

Cloud9
Cloud9
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Scientific Breakthrough in Fibromyalgia Mice study Empty Scientific Breakthrough in Fibromyalgia Mice study

Post by Cloud9 Mon Aug 09, 2021 7:51 am

Fibromyalgia may be a condition of the immune system not the brain – study

Fibromyalgia – a poorly understood condition that causes widespread pain throughout the body and extreme tiredness – may be caused by be an autoimmune response that increases the activity of pain-sensing nerves throughout the body.

The findings, published in the Journal of Clinical Investigation, challenge the widely held view that the condition originates in the brain, and could pave the way for more effective treatments for the millions of people affected.


Bottom line-
The development of new therapies has also been hampered by a limited scientific understanding of what causes the condition in the first place, but this could change with the discovery that the immune system is involved.

Andersson and his colleagues harvested blood from 44 people with fibromyalgia and injected purified antibodies from each of them into different mice. The mice rapidly became more sensitive to pressure and cold, and displayed reduced grip strength in their paws. Animals injected with antibodies from healthy people were unaffected.

Prof Camilla Svensson from the Karolinska Institute in Sweden, who was also involved in the study, said: “Antibodies from people with fibromyalgia living in two different countries, the UK and Sweden, gave similar results, which adds enormous strength to our findings.”

The mice recovered once the antibodies had been cleared from their systems, which took a few weeks. This suggests that therapies such as plasma-exchange, which are designed to reduce antibody levels and are available for other autoimmune disorders, such as myasthenia gravis, may be effective in fibromyalgia patients.

Source


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Scientific Breakthrough in Fibromyalgia Mice study Jl2e89

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Cloud9
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Scientific Breakthrough in Fibromyalgia Mice study Empty Re: Scientific Breakthrough in Fibromyalgia Mice study

Post by Cloud9 Mon Aug 09, 2021 7:53 am

@Eagle

Hope you see this.

Praying in future this crippling disease will have real
Effective treatments so that people can throw out the morphine, pills, crutches/wheelchairs and be able to live a functional life again. This disease is hell. But I am glad that scientists are not giving up on trying to het to the bottom of the causes


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Scientific Breakthrough in Fibromyalgia Mice study Jl2e89

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