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Scientists create healthy mice with two mothers

Cloud
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Scientists create healthy mice with two mothers Empty Scientists create healthy mice with two mothers

Post by Cloud Sat Oct 27, 2018 4:28 pm

Scientists create healthy mice with two mothers News-mouse-lab
The mice were born to two mothers and no father. Image Credit: CC BY-SA 2.0 Rama

The breakthrough could eventually make it possible for human same-sex couples to have their own children.
While mice with same-sex parents have been born before, previous efforts were only able to produce animals with severe defects that didn't live very long.

This time though, the offspring were not only healthy but were even able to have offspring of their own.

The research, which was carried out by Wei Li and colleagues at the Chinese Academy of Sciences, sought to answer the long-running question of why mammals require equal genetic contributions from both a mother and father in order to create a viable offspring.

Some other species, such as hammerhead sharks and komodo dragons, can reproduce without requiring any genetic contribution from a father.

In mammals, the most significant hurdle to same-sex reproduction lies in what is known as 'imprinting' - a phenomenon in which only a certain number of genes from the mother and a certain number of genes from the father are ever switched on.

To overcome this, scientists used CRISPR gene editing to make some of the genetic material from the two female parents more 'male' in terms of its imprinting pattern.

"The authors have made an extremely important step forward in understanding why mammals can only reproduce sexually," said Christophe Galichet from the The Francis Crick Institute in London.


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Dragon
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Scientists create healthy mice with two mothers Empty Re: Scientists create healthy mice with two mothers

Post by Dragon Tue Oct 30, 2018 10:58 pm

"Using gene editing and stem cells, researchers in China have helped mice of the same sex bear pups."

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A recent scientific development could lead to new infertility treatments and bring same-sex couples one step closer to conceiving a child with both their DNA.

In a medical first, two mothers have carried the same baby: Ashleigh Coulter gave birth to a son both she and her wife Bliss Coulter carried, thanks to a breakthrough method of in vitro fertilization.

The method, called Effortless Reciprocal IVF, allowed Bliss to incubate her own embryo. Then, the embryo was placed inside Ashleigh, where it grew until she delivered: In June, Stetson was born at a healthy 8 pounds, 3 ounces.


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